Search
Now showing items 1-9 of 9
Lipoprotein lipase gene polymorphism and lipid profile in coronary artery disease
(COLL AMER PATHOLOGISTS, 2004)
Context.-Lipoprotein lipase (LPL) plays a central role in lipid metabolism hydrolyzing triglyceride in chylomicrons and very-low-density lipoproteins. The PvuII polymorphic variant of LPL gene is common and might affect ...
Protective effects of a calcium channel blocker on apoptosis in thymus of neonatal STZ-diabetic rats
(Elsevier GMBH Urban & Fischer Verlag, 2005)
Streptozotocin (STZ) is known to induce insulin-dependent diabetes in experimental animals. In STZ-induced diabetes atrophy of the thymus is caused by elevated intracellular calcium levels leading to apoptosis. Hyperglycemia ...
Polymorphisms at the ligand binding site of the vitamin D receptor gene and osteomalacia
(Hindawi Ltd, 2005)
Vitamin D receptor (VDR) gene polymorphisms have been suggested as possible determinants of bone mineral density (BMD) and calcium metabolism. In this study our aim was to determine whether there is an association between ...
DNA polymorphism of Pvu II site in the lipoprotein lipase gene in patients with non-insulin dependent diabetes mellitus
(Wiley, 2005)
We studied the effect of variation at the lipoprotein lipase (LPL) gene locus on the susceptibility of individuals with non-insulin dependent diabetes mellitus (NIDDM) in a population of 110 NIDDM patients and 91 controls. ...
Genetic variations of the apolipoprotein B gene in Turkish patients with coronary artery disease
(Taylor & Francis Ltd, 2005)
Background: The results of studies that clarify the association of genetic markers at the apolipoprotein B (apo B) gene (EcoRI and XbaI polymorphisms) with coronary artery disease (CAD) are not consistent and suggest that ...
Thiols malonaldehyde status in the Turkish and total antioxidant patients with type 2 diabetes mellitus
(Tohoku Univ Medical Press, 2003)
Non-insulin-dependent (Type 2) diabetes mellitus (NIDDM) is a risk factor for cardiovascular diseases (CVD). Oxidative stress mechanisms are often reported to be implied in type 2 diabetes mellitus. In order to determine ...
Vitamin D receptor alleles bone mineral density and turnover in postmenopausal osteoporotic and healthy women
(Karger, 2004)
Objective: Vitamin D receptor (VDR) gene polymorphisms and bone metabolic markers were investigated as potential genetic markers for osteoporosis in postmenopausal Turkish women. The relationship between their VDR gene ...
Effect of abdominal obesity on insulin resistance and the components of the metabolic syndrome: Evidence supporting obesity as the central feature
(F D-Communications Inc., 2003)
Background: Metabolic syndrome includes abdominal obesity diabetes type 2 hypertension dyslipidemia derangements of fibrinolysis and atherosclerosis. Since abdominal obesity is one of the major components of the insulin ...
Apolipoprotein B gene variants are involved in the determination of blood glucose and lipid levels in patients with non-insulin dependent diabetes mellitus
(Wiley, 2006)
We have examined the frequency of the EcoRI XbaI and MspI RFLPs of the apolipoprotein B (apo 13) gene in I 10 type 2 diabetic patients and 9 1 healthy control subjects in order to ascertain whether variation in this gene ...