Browsing Mühendislik ve Doğa Bilimleri Fakültesi by Title
Now showing items 322-341 of 750
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A hesitant fuzzy linguistic terms set-based AHP-TOPSIS approach to evaluate ERP software packages
(Emerald Group Publishing Ltd, 2020)Purpose In this paper, two popular multiple-criteria decision-making (MCDM) methods with hesitant fuzzy logic approach; hesitant fuzzy analytic hierarchy process (hesitant F-AHP) and hesitant fuzzy the technique for order ... -
A heuristic approach for allocation of data to RFID tags: A data allocation knapsack problem (DAKP)
(Pergamon-Elsevier Science Ltd, 2012)Durable products and their components are increasingly being equipped with one of several forms of automatic identification technology such as radio frequency identification (RFID). This technology enables data collection, ... -
High-pass/low-pass section design for 0 degrees-360 degrees lumped-element phase shifters via the real frequency technique
(TUBITAK Scientific & Technical Research Council Turkey, 2017)In this paper an algorithm based on the real frequency technique (RFT) is proposed to design high-pass and low-pass sections of a 0 degrees-360 degrees wide range lumped-element phase shifter. The switching process however ... -
Histone Deacetylase Inhibition Activity and Molecular Docking of (E )-Resveratrol: Its Therapeutic Potential in Spinal Muscular Atrophy
(Wiley, 2009)Spinal muscular atrophy is an autosomal recessive motor neuron disease that is caused by mutation of the survival motor neuron gene (SMN1) but all patients retain a nearly identical copy SMN2. The disease severity correlates ... -
A historical assessment of Turkey's natural gas import vulnerability
(Pergamon-Elsevier Science Ltd, 2018)This article aims at evaluating the historical determinants and implications of Turkey's natural gas import dependency. We implement principle component analysis (PCA) methodology to construct a natural gas import vulnerability ... -
Holocene climate forcings and lacustrine regime shifts in the Indian summer monsoon realm
(Wıley, 2020)Extreme climate events have been identified both in meteorological and long-term proxy records from the Indian summer monsoon (ISM) realm. However, the potential of palaeoclimate data for understanding mechanisms triggering ... -
Homology modeling andin silicodesign of novel and potential dual-acting inhibitors of human histone deacetylases HDAC5 and HDAC9 isozymes
(2020)Histone deacetylases (HDACs) are a group of enzymes that have prominent and crucial effect on various biological systems, mainly by their suppressive effect on transcription. Searching for inhibitors targeting their ... -
Homology modeling of human histone deacetylase 10 and design of potential selective inhibitors
(Taylor & Francis Inc, 2019)Histone deacetylases (HDACs) are implicated in the pathology of various cancers, and their pharmacological blockade has proven to be promising in reversing the malignant phenotypes. However, lack of crystal structures of ... -
Hourly electricity demand forecasting using Fourier analysis with feedback
(Elsevıer, 2020)Whether it be long-term, like year-ahead, or short-term, such as hour-ahead or day-ahead, forecasting of electricity demand is crucial for the success of deregulated electricity markets. The stochastic nature of the demand ... -
How an Inhibitor Bound to Subunit Interface Alters Triosephosphate Isomerase Dynamics
(Cell Press, 2015)The tunnel region at triosephosphate isomerase (TIM)'s dimer interface distant from its catalytic site is a target site for certain benzothiazole derivatives that inhibit TIM's catalytic activity in Trypanosoma cruzi the ... -
Human dopamine transporter: the first implementation of a combined in silico/in vitro approach revealing the substrate and inhibitor specificities
(Taylor & Francis Inc, 2019)Parkinson's disease (PD) is characterized by the loss of dopamine-generating neurons in the substantia nigra and corpus striatum. Current treatments alleviate PD symptoms rather than exerting neuroprotective effect on ... -
A hybrid approach to concept selection through fuzzy analytic network process
(Pergamon-Elsevier Science Ltd, 2009)Evaluating conceptual design alternatives in a new product development (NPD) environment has been one of the most critical issues for many companies which try to survive in the fast-growing world markets. Therefore most ... -
A hybrid approach to machine-tool selection through AHP and simulation
(Taylor & Francis, 2007)The selection process of a machine tool has been a critical issue for companies for years because the improper selection of a machine tool might cause many problems having a negative effect on productivity precision ... -
Hybrid MEMS-Based molecular communication system
(Institute of Electrical and Electronics Engineers Inc., 2019)In this paper, we consider a molecular communication link integrated in a micro-electro mechanical system (MEMS) based environment. We apply acoustic tweezing techniques to the molecular communication system to increase ... -
Hybrid MPI plus UPC parallel programming paradigm on an SMP cluster
(TUBITAK Scientific & Technical Research Council Turkey, 2012)The symmetric multiprocessing (SMP) cluster system which consists of shared memory nodes with several multicore central processing units connected to a high-speed network to form a distributed memory system is the most ... -
Identification of Alternative Allosteric Sites in Glycolytic Enzymes for Potential Use as Species-Specific Drug Targets
(Frontiers Media, 2020)Three allosteric glycolytic enzymes, phosphofructokinase, glyceraldehyde-3 phosphate dehydrogenase and pyruvate kinase, associated with bacterial, parasitic and human species, were explored to identify potential allosteric ... -
Identification of potential inhibitors of human methionine aminopeptidase (type II) for cancer therapy: Structure-based virtual screening, ADMET prediction and molecular dynamics studies
(Elsevier, 2020)Methionine Aminopeptidases MetAPs are divalent-cofactor dependent enzymes that are responsible for the cleavage of the initiator Methionine from the nascent polypeptides. MetAPs are classified into two isoforms: namely, ... -
Identification of potential isoform-selective histone deacetylase inhibitors for cancer therapy: a combined approach of structure-based virtual screening ADMET prediction and molecular dynamics simulation assay
(Taylor & Francis Inc, 2018)Histone deacetylases (HDACs) have gained increased attention as targets for anticancer drug design and development. HDAC inhibitors have proven to be effective for reversing the malignant phenotype in HDAC-dependent cancer ... -
IEEE 802.15.4a Based Ultra Wideband Systems for Coexistence with Primary Users
(IEEE, 2015)Peaceful coexistence is a major implementation issue for both cognitive radios and ultra wideband (UWB) systems. Accordingly the UWB impulse radio (UWB-IR) based Wireless Personal Area Network (WPAN) standard IEEE 802.15.4a ... -
IEEE 802.15.7r1 Reference Channel Models for Visible Light Communications
(IEEE-Inst Electrical Electronics Engineers Inc, 2017)The IEEE has established the standardization group 802.15.7r1 "Short Range Optical Wireless Communications", which is currently in the process of developing a standard for visible light communication (VLC). As with any ...