Cation Effect on Slow Release from Alginate Beads: A Fluorescence Study

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Date
2014
Authors
Kaygusuz, Hakan
Erim, F. Bedia
Pekcan, Önder
Evingür, Gülşen Akin
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Volume Title
Publisher
Springer/Plenum Publishers
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Abstract
In this study spherical alginate beads containing pyranine (P-y) as a fluorescence probe were prepared by ionotropic gelation of a sodium alginate solution. The steady state fluorescence technique was used to study pyranine release from the alginate beads crosslinked with calcium barium and aluminum ions respectively. The slow release of P-y was observed with the time drive mode of the spectrophotometer at 512 nm. Fluorescence emission intensity (I-p) from P-y was monitored during the release process and the encapsulation efficiency (EE) of pyranine from the alginate beads was calculated. The Fickian Diffusion model was used to measure the release coefficients D-sl. It was seen that the slow release coefficients of pyranine from the alginate beads crosslinked with Ca2+ Ba2+ and Al3+ ions increased in the following order: D-sl (Al3+)> D-sl (Ca2+)> D-sl (Ba2+). In contrast the initial amount of pyranine and EE into the beads showed the reverse behavior.
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Keywords
Slow release, Metal ions, Fluorescence, Encapsulation efficiency, Pyranine
Turkish CoHE Thesis Center URL
Citation
16
WoS Q
N/A
Scopus Q
Q3
Source
Volume
24
Issue
1
Start Page
161
End Page
167