Cation Effect on Slow Release from Alginate Beads: A Fluorescence Study
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Date
2014
Authors
Kaygusuz, Hakan
Erim, F. Bedia
Pekcan, Önder
Evingür, Gülşen Akin
Journal Title
Journal ISSN
Volume Title
Publisher
Springer/Plenum Publishers
Abstract
In this study spherical alginate beads containing pyranine (P-y) as a fluorescence probe were prepared by ionotropic gelation of a sodium alginate solution. The steady state fluorescence technique was used to study pyranine release from the alginate beads crosslinked with calcium barium and aluminum ions respectively. The slow release of P-y was observed with the time drive mode of the spectrophotometer at 512 nm. Fluorescence emission intensity (I-p) from P-y was monitored during the release process and the encapsulation efficiency (EE) of pyranine from the alginate beads was calculated. The Fickian Diffusion model was used to measure the release coefficients D-sl. It was seen that the slow release coefficients of pyranine from the alginate beads crosslinked with Ca2+ Ba2+ and Al3+ ions increased in the following order: D-sl (Al3+)> D-sl (Ca2+)> D-sl (Ba2+). In contrast the initial amount of pyranine and EE into the beads showed the reverse behavior.
Description
Keywords
Slow release, Metal ions, Fluorescence, Encapsulation efficiency, Pyranine
Turkish CoHE Thesis Center URL
Citation
16
WoS Q
N/A
Scopus Q
Q3
Source
Volume
24
Issue
1
Start Page
161
End Page
167