Browsing Tez Koleksiyonu by Title
Now showing items 520-539 of 1348
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The impact of youth academies on financial & sporting success of the leading associations in European football
(Kadir Has Üniversitesi, 2022-06)In this study, the financial performances of the top leagues in UEFA's associations in terms of total assets and in many other aspects between 2013-18 were examined with the macroeconomic conditions of the countries they ... -
The impacts of foreign direct investment inflows in Bric conturies
(Kadir Has Üniversitesi, 2013)Over the 1990s, most developing countries considered a series of market reforms, including the opening of their capital accounts. The role of Foreign Direct Investment (FDI) in the growth process has been recognized by ... -
The impacts of the securitization of migration: The case of Mexican undocumented immigrants in the united states since 1986
(Kadir Has Üniversitesi, 2018)In the discipline of International Relations, security used to refer exclusively to the field of military power. However, with the end of the Cold War, the orthodox concept has considerably broadened to include non-military ... -
Implementation of information technology infrastructure library (ITIL) processes
(Kadir Has Üniversitesi, 2011)Several frameworks tools and standards have been included in iT management systems in organizations such as COBiT CMMS. These days iT management is focusing particularly on the de facto standard iTiL for implementing iT ... -
Implementation of Pci-Dss V3.0 information security standards
(Kadir Has Üniversitesi, 2015)Way of doing business has changed with rapid spread of the internet and mobile devices and payment systems must keep up with that. Most of the monetary transactions are done electronically and percentage of internet trade ... -
Importance of Data Preprocessing For Improving Classification Performance on CAC Data Set
(Kadir Has Üniversitesi, 2012)Data Mining usage in Health Sector increased much in this decade because of the need -
Importance of LNG in Turkish natural gas supply security
(Kadir Has Üniversitesi, 2019)The Natural Gas has been increasing its share of usage day by day due to the technologic developments, low carbon emission, increasing natural gas reserve in the fossil-based energy market. Nowadays, the share of natural ... -
The importance Of The North Caucasus For The Black Sea’s Regional Security
(Kadir Has Üniversitesi, 2018)Since ancient times, the North Caucasus lands have been home to many ethnic cultures, societies, and states. Today it is a gateway, which opens Russia to the South Caucasus, Asia and the Middle East and a buffer zone and ... -
Improving the accuracy of indoor positioning system
(Kadir Has Üniversitesi, 2019)Indoor positioning applications needs high accuracy and precision to overcome the existing obstacles and relatively small areas. There are several methods which could be used to locate an object or people in an indoor ... -
Improving the quality of recommender systems in e-commerce platforms
(Kadir Has Üniversitesi, 2021)Especially Covid-19 pandemic process, which has taken the world by storm, has shed a clear light on the place of e-commerce, which is already increasing its influence with the globalizing world, in the future world of ... -
In search of a comprehensive approach to improve civil-military cooperation: The cases of IFOR, SFOR, KFOR and ISAF
(Kadir Has Üniversitesi, 2020)1990'lı yılların başlarından itibaren Yugoslavya'nın dağılması sürecinde yaşanan savaş ve müteakiben önce Bosna-Hersek ve daha sonra Kosova'da icra edilen Barış Harekâtları sivil ve asker oluşumların harekât alanında daha ... -
In silico design and modeling of coumarin derivatives as selective monoamine oxidase a inhibitors
(Kadir Has Üniversitesi, 2014)Selective and reversible inhibition of Monoamine Oxidase (MAO) isoenzymes has an important place in treatment of various neurological disorders. Out of the two isoforms of Monoamine Oxidase enzymes inhibition of MAO-A have ... -
In silico design and modeling of peptidomimetic drug candidates for methionine aminopeptidase 2 enzyme for prevention of cancer
(Kadir Has Üniversitesi, 2019)Birçok hastalık bir araya gelerek kanseri oluşturur. Kanser hücreleri kontrolsüz bir şekilde bölünür. Kanserde hücre çoğalması anormaldir. Yıllar içinde 200'den fazla kanser çeşidi teşhis edilmiştir. Bazı faktörler kansere ... -
In silico design of novel and highly selective cyclooxygenase-2 inhibitors
(Kadir Has Üniversitesi, 2014)For many years, prevention of inflammation is achieved by inhibition of both cyclooxygenase (COX) enzymes; the eventual outcome is gastrointestinal toxicity. Selective inhibitor design for COX-2 initialized just after ... -
In silico design of selective monoamine Oxidase B inhibitors using indane ring
(Kadir Has Üniversitesi, 2013)in the present work 209952 analogs of an indane scaffold were created using various fragment moieties at different position of indane ring. CHEMPLP module of GOLD program is utilized in the screening process. in order to ... -
In silico design of selective neuronal nitric oxide synthase inhibitors in order to prevent neurodegenerative diseases
(Kadir Has Üniversitesi, 2013)Nitric Oxide syntheses (NOS) are the family of enzymes which catalyzes the oxidation L-Arginine amino acid to nitric oxide molecule (NO) L-citrulline. Mammals contain three different NOS isozymes: Neuronal NOS (nNOS, in ... -
In silico designing of isoform-selective inhibitors against class IIA histone deacetylases
(Kadir Has Üniversitesi, 2021)The fundamental cause of human cancer is strongly influenced by down- or upregulations of epigenetic factors. Upregulated histone deacetylases (HDAC) have been shown to be effectively neutralized by the action of HDACs ... -
In silico identification of physiological substrates and inhibitors of serum paraoxonase 1 enzyme
(Kadir Has Üniversitesi, 2014)Paraoxonase 1 (PON1) as an important antioxidant enzyme against oxidative stress has been implicated in the pathogenesis of a number of disorders including cancer cardiovascular and several other diseases. Although there ... -
In Silico Inhibitor Design For Monomine Oxidase A And B Isozymes
(Kadir Has Üniversitesi, 2012)in this thesis study MAO-A and MAO-B isozymes are selected as target enzymes that have important role of regulation of diseases such as ..Parkinson Alzheimer and depression... MAO isozymes which catalyze the oxidation of ... -
In silico modeling of dopamine transporter and design of novel neuroprotective drugs for Parkinson's disease
(Kadir Has Üniversitesi, 2017)Parkinson hastalıgı (PH), substantia nigra (SN) ve corpus striatum (CS) bolgelerinde dopamin ureten noronların kaybedilmesi ile karakterize edilen bir olgudur. Yaygın olarak uygulanan tedavi dopamin noronlarının kaybolmalarının ...