Aryl Butenoic Acid Derivatives as a New Class of Histone Deacetylase Inhibitors: Synthesis in Vitro Evaluation and Molecular Docking Studies
| dc.contributor.author | Esiyok, Peruze Ayhan | |
| dc.contributor.author | Seven, özlem | |
| dc.contributor.author | Eymur, Guluzar | |
| dc.contributor.author | Tatar, Gamze Bora | |
| dc.contributor.author | Erden, Didem Dayangaç | |
| dc.contributor.author | Yelekçi, Kemal | |
| dc.contributor.author | Yurter, Hayat | |
| dc.contributor.author | Demir, Ayhan S. | |
| dc.contributor.author | Ayhan, Peruze Eşıyok | |
| dc.date.accessioned | 2019-06-27T08:03:13Z | |
| dc.date.available | 2019-06-27T08:03:13Z | |
| dc.date.issued | 2014 | |
| dc.description.abstract | New aryl butenoic acid derivatives have been synthesized by combining hydroxy- or methoxy-substituted phenyl rings as the capping group with a double bond in the short linker as well as metal binding groups enoic ester and salts bearing either methyl or morpholine. These compounds have been shown to possess promising histone deacetylase inhibition activities via in vitro fluorometric assay and molecular docking studies. | en_US] |
| dc.identifier.doi | 10.3906/kim-1305-56 | en_US |
| dc.identifier.issn | 1300-0527 | |
| dc.identifier.issn | 1303-6130 | |
| dc.identifier.scopus | 2-s2.0-84897899399 | en_US |
| dc.identifier.uri | https://hdl.handle.net/20.500.12469/757 | |
| dc.identifier.uri | https://doi.org/10.3906/kim-1305-56 | |
| dc.identifier.uri | https://search.trdizin.gov.tr/en/yayin/detay/163341 | |
| dc.language.iso | en | en_US |
| dc.publisher | Scientific Technical Research Council Turkey-Tubitak | en_US |
| dc.relation.ispartof | TURKISH JOURNAL OF CHEMISTRY | |
| dc.rights | info:eu-repo/semantics/openAccess | en_US |
| dc.subject | Histone deacetylase inhibition activity | en_US |
| dc.subject | Aryl butenoic acid derivatives | en_US |
| dc.subject | Molecular docking | en_US |
| dc.subject | Tıbbi Araştırmalar Deneysel | |
| dc.subject | Biyokimya Ve Moleküler Biyoloji | |
| dc.subject | Kimya, Tıbbi | |
| dc.title | Aryl Butenoic Acid Derivatives as a New Class of Histone Deacetylase Inhibitors: Synthesis in Vitro Evaluation and Molecular Docking Studies | en_US |
| dc.type | Article | en_US |
| dspace.entity.type | Publication | |
| gdc.author.id | 0000-0002-0052-4926 | |
| gdc.author.id | 0000-0002-5883-0643 | |
| gdc.author.institutional | Yelekçi, Kemal | en_US |
| gdc.bip.impulseclass | C5 | |
| gdc.bip.influenceclass | C5 | |
| gdc.bip.popularityclass | C5 | |
| gdc.coar.access | open access | |
| gdc.coar.type | text::journal::journal article | |
| gdc.collaboration.industrial | false | |
| gdc.description.department | Fakülteler, Mühendislik ve Doğa Bilimleri Fakültesi, Biyoinformatik ve Genetik Bölümü | en_US |
| gdc.description.departmenttemp | [Yelekci, Kemal] Kadir Has Üniversitesi, İstanbul, Türkiye; [Demir, Ayhan Sıtkı; Seven, Özlem; Ayhan, Peruze Eşıyok; Eymur, Gülüzar] Orta Doğu Teknik Üniversitesi, Fen Edebiyat Fakültesi, Kimya Bölümü, Ankara, Türkiye; [Erden, Didem Dayangaç; Bora, Gamze Tatar; Yurter, Hayat Erdem] Hacettepe Üniversitesi Tıp Fakültesi Tıbbi Biyoloji Anabilim Dalı, Ankara, Türkiye | |
| gdc.description.endpage | 344 | |
| gdc.description.issue | 2 | |
| gdc.description.publicationcategory | Makale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı | en_US |
| gdc.description.scopusquality | Q3 | |
| gdc.description.startpage | 338 | en_US |
| gdc.description.volume | 38 | en_US |
| gdc.description.wosquality | Q3 | |
| gdc.identifier.openalex | W2144253137 | |
| gdc.identifier.trdizinid | 163341 | |
| gdc.identifier.wos | WOS:000332942200016 | en_US |
| gdc.index.type | WoS | |
| gdc.index.type | Scopus | |
| gdc.index.type | TR-Dizin | |
| gdc.oaire.accesstype | BRONZE | |
| gdc.oaire.diamondjournal | false | |
| gdc.oaire.impulse | 0.0 | |
| gdc.oaire.influence | 2.670914E-9 | |
| gdc.oaire.isgreen | true | |
| gdc.oaire.keywords | Histone deacetylase inhibition activity | |
| gdc.oaire.keywords | Molecular docking | |
| gdc.oaire.keywords | Aryl butenoic acid derivatives | |
| gdc.oaire.popularity | 1.4967627E-9 | |
| gdc.oaire.publicfunded | false | |
| gdc.oaire.sciencefields | 0103 physical sciences | |
| gdc.oaire.sciencefields | 01 natural sciences | |
| gdc.openalex.collaboration | National | |
| gdc.openalex.fwci | 0.0 | |
| gdc.openalex.normalizedpercentile | 0.11 | |
| gdc.opencitations.count | 2 | |
| gdc.plumx.crossrefcites | 2 | |
| gdc.plumx.mendeley | 15 | |
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| gdc.relation.journal | Turkish Journal of Chemistry | |
| gdc.scopus.citedcount | 3 | |
| gdc.virtual.author | Yelekçi, Kemal | |
| gdc.wos.citedcount | 2 | |
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